Visual Field Restoration in Patients With Post-stroke Homonymous Hemianopsia

Not Applicable

Terminated

• Conditions: Hemianopsia
• Interventions: Other: stimulation of the blind visual field

• Registration Number: NCT02886663
• Lead Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary

This study will assess the effectiveness of a stimulus, in the blind field of hemianopsic patients, to restore the vision of patients with homonymous hemianopsia consecutive to stroke (unilateral occipital lesion). Hemianopsia occurs in 30% of strokes regardless of the cerebral localization and in 60% of stroke interesting the territory of the posterior cerebral artery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-08-29
• Study First Submitted QC: 2016-08-29
• Study First Posted: 2016-09-01
• Study Start: 2016-12-13
• Primary Completion: 2019-11-25
• Study Completion: 2019-11-25
• Status Verified: 2019-12
• Last Update Submitted: 2019-12-11
• Last Update Posted: 2019-12-13

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 9

Inclusion Criteria

• Presence of an homonymous visual field amputation after vascular retrochiasmatic lesion of the occipital region (visual cortex alone or with optical radiations or with other associated occipital areas)
• inclusion 3 months to 36 months after stroke
• Patients aged 18 years and older

Exclusion criteria:

• Brain injury history
• Severe neuropsychological, psychiatric or behavioral disorder
• Severe eye disorder or visual impairment (visual acuity less than 3/10)
• Progressive eye disorder (cataracts or glaucoma)
• insufficient French language proficiency to understand the questionnaires and rehabilitation tasks
• patient under legal protection
• patient's opposition to participate in the study
• no medical insurance coverage
• pregnant pr breastfeeding patient

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
immediate rehabilitation	stimulation of the blind visual field	-
delayed rehabilitation	stimulation of the blind visual field	-

Primary Outcome Measures

Name	Time	Method
change in the sensitivity of detection of a visual stimulus after rehabilitation	change from baseline sensitivity at week 22	change in the mean number of points where the sensitivity is lower than 15db in each contralesional hemifield, before and after rehabilitation

Trial Locations

Locations (1)

Fondation Ophtalmologique Adolphe de Rothschild; 🇫🇷 Paris, France