Effect of exercise on mucus rheology and inspiratory/expiratory flow-volume relationships in people with Cystic Fibrosis

Phase 2

Completed

• Conditions: Cystic Fibrosis; Human Genetics and Inherited Disorders - Cystic fibrosis

• Registration Number: ACTRN12605000422628
• Lead Sponsor: SWSAHS

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-09-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

Diagnosed with cystic fibrosis

Exclusion Criteria

Post lung transplant; infected with burkholderia cepacia complex; not clinically stable

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mucus rheology. Samples collected are control-separated by 20 minutes.[At pre-exercise, immediately post-exercise and 20 minutes post-exercise];Inspiratory and expiratory flow-volume relationships[Recorded throughout peak and endurance exercise tests]

Secondary Outcome Measures

Name	Time	Method
Subjective ease of expectoration[Immediately pre-intervention, immediately post-intervention, 20 minutes post-intervention];Comparison of bike versus treadmill exercise capacity and effect on mucus rheology and flow-volume relationships.[Immediately pre-intervention, immediately post-intervention, 20 minutes post-intervention];Comparison of peak and endurance exercise capacity.[Measurements taken each minute throughout the 20 minutes of endurance exercise and throughout the peak exercsise test.]