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临床试验/NCT05882942
NCT05882942已完成不适用

Effects of Matcha Green Tea on Heart Rate Variability, Substrate Oxidation and Cardiovascular Response at Rest and During Moderate-intensity Exercise in Females

University of Chichester3 个研究点 分布在 1 个国家目标入组 8 人开始时间: 2023年3月3日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
8
试验地点
3
主要终点
Cardiac output

研究概览

简要总结

Intake of the green tea catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. This research will expand the insight on the effects by Matcha green tea supplementation and address the effects on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

详细描述

Intake of the catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. EGCG is the most abundant and potent bioactive compound (50-80% of the total catechin content) found in Matcha green tea (MGT) and is usually consumed as a drink or in a capsulated from unfermented tea leaves. MGT polyphenols have antioxidant and anti-inflammatory properties, providing numerous health benefits, such as the reduced risk of type 2 diabetes and obesity. MGT supplementation (3g over a 24hr period) has been shown to enhance fat oxidation during 30-min brisk walking as well as lower respiratory exchange ratio in females. Understanding the effectiveness of the bioactive compounds found in natural food sources in improving human health is key to informing the general population and the public health policies preceding them; the daily consumption of drinks and food naturally high in EGCG content could be recommended as an essential part of a healthy lifestyle. This research will expand the insight on Matcha green tea supplementation address the effect on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • non-smokers
  • not taking any supplements
  • no known allergy to green tea

排除标准

  • known high blood pressure
  • on medication

结局指标

主要结局

Cardiac output

时间窗: Three weeks

Measurement of cardiac output in liters per minute

Fat oxidation

时间窗: Three weeks

Measurement of fat oxidation in grams/minute

Carbohydrate oxidation

时间窗: Three weeks

Measurement of carbohydrate oxidation in grams/minute

Stroke volume

时间窗: Three weeks

Measurement of stroke volume in milliliters

Heart rate variability

时间窗: Three weeks

Measurement of root mean square of standard deviation of RR intervals

Total peripheral resistance

时间窗: Three weeks

Measurement of total peripheral resistance in (mmHg x min) / mL

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mark Eilisabeth Willems

Professor of Exercise Physiology

University of Chichester

研究点 (3)

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