Effects of Green Tea Extract on Obese Women With High Level of LDL
Phase 3
Completed
- Conditions
- ObeseHyperlipidemia
- Registration Number
- NCT02116517
- Lead Sponsor
- National Yang Ming Chiao Tung University
- Brief Summary
Green tea is one of the most popular beverages in the world. It is believed to have beneficial effect in prevention and treatment of many diseases, one of which is reducing LDL-C. The aim of the study is to examine the effect of supplement containing GTE on obese with high LDL level.
- Detailed Description
Randomized, double-blind, crossover placebo-controlled clinical trial
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 73
Inclusion Criteria
- age between 18 and 65 years
- body mass index (BMI) >= 27 kg/m2
- fasting low-density-lipoprotein cholesterol (LDL) >= 130mg/dl and (4) willing to participate in this trial.
Exclusion Criteria
- serum alanine transaminase > 80 U/L
- serum creatinine > 1.8 mg/dl
- breast feeding or pregnancy
- heart failure, acute myocardial infarction, stroke, heavy injury
- any other conditions not suitable for trial as evaluated by the physician. -
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method percentage of reduction of LDL-C 6 weeks of treatment level of LDL-C before intervention minus level of LDL-C after intervention equal to reduction of LDL-C, percentage of reduction of LDL-C equal to the level of reduction of LDL-C divided by level of LDL-C before intervention
- Secondary Outcome Measures
Name Time Method HDL-C 6 weeks serum level of high density lipoprotein cholesterol
Trial Locations
- Locations (1)
Taipei City Hospital
🇨🇳Taipei, Taiwan
Taipei City Hospital🇨🇳Taipei, Taiwan