Efficacy of laser in facial rejuvinatio
Phase 2
- Conditions
- Skin Rejuvination.Other specified disorders of skin and subcutaneous tissue
- Registration Number
- IRCT2015120320468N3
- Lead Sponsor
- Skin Research Center, Shahid Beheshti University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 35
Inclusion Criteria
females between 35 and 75years of age ;patients with mild to moderate facial rhytides at rest Exclusion criteria :males;females younger than 35 yerars old;pregnancy and lactatation;cosmetic procedures affecting the treatment area (e.g.,botulinum toxin,dermabrasion, chemical peeling, laser surgery, or face-lift)within the last 6months;oral isotretinoin within the last 6months; history of keloid formation,connective tissue disorders,major underlying disease,diabetes, uncontrolled hypertension, active infection in face area, personal history of skin cancer in face,unrealistic expectation,sensitivity to tetracaine or lidocaine
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skin Elasticiy. Timepoint: before intervention,before each laser sessions,3 months after last laser. Method of measurement: resonance running time/reviscometer.;Improvement of facial rythides. Timepoint: before intervention,before each laser sessions,3 months after last laser. Method of measurement: rate of improvement measured by comparing photograph by a dermatologist.;Patient satisfaction. Timepoint: 1month after session 1&2-three month after session3. Method of measurement: questionare.
- Secondary Outcome Measures
Name Time Method ?Duration of side effects. Timepoint: one week after each session. Method of measurement: number of days.;Side effects(pain-burning and stinging-erythem-edema-bulla-bleeding-crust formation-hypopigmentation-hyperpigmentation-scar-atrophy). Timepoint: one week after each session. Method of measurement: patient questionnaire,examination by a dermatologist.