Blood Pressure Responses to Isometric Blood Flow Restriction Exercise
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Blood Pressure
- Sponsor
- University of Texas at Austin
- Enrollment
- 21
- Locations
- 1
- Primary Endpoint
- Brachial artery diameter evaluated by an ultrasound machine
- Status
- Completed
- Last Updated
- 10 months ago
Overview
Brief Summary
The goal of this interventional study is to evaluate the acute impact of isometric blood flow restriction (BFR) exercise on blood pressure and other cardiovascular functions in healthy young adult volunteers. The main question it aims to answer is:
The investigators hypothesize that isometric BFR exercise with a wide-rigid cuff would lead to greater blood pressure and other cardiovascular responses and that these cardiovascular responses would be greater under isometric BFR exercise with narrow-elastic bands compared with the control condition (no cuff).
Participants will perform isometric exercises in 3 laboratory visits with different exercise conditions) no cuff control 2) BFR with wide-rigid cuff 3) BFR with narrow-elastic band.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Apparently healthy young adults aged between 18 - 40 years old and signed the informed consent.
Exclusion Criteria
- •Abnormal clotting times
- •Acid-base imbalance/acidosis
- •Arterial calcification
- •Atherosclerotic vessels
- •Cardiopulmonary conditions
- •Dialysis/central venous access
- •General/local infection
- •High intracranial pressure
- •Hip, pelvis, or femur fracture
- •History of venous thromboembolism
Outcomes
Primary Outcomes
Brachial artery diameter evaluated by an ultrasound machine
Time Frame: Before and 20 minutes after exercise
Brachial artery diameter will be measured by an ultrasound machine to calculate flow-mediated dilation (FMD)
Heart rate
Time Frame: 20 minutes
Monitor heart rate continuously before, during, and after exercise
Systolic blood pressure and diastolic blood pressure
Time Frame: 20 minutes
Beat-by-beat (both systolic and diastolic blood pressure) blood pressure before, during, and after exercise