Medication Safety of Elderly Patients in Hospital and Ambulatory Setting

Not Applicable

Completed

• Conditions: Medication Safety; Pharmaceutical Care; Hospital Readmission; Elderly; Health Services for the Aged
• Interventions: Other: Pharmaceutical Care Service

• Registration Number: NCT01578525
• Lead Sponsor: RWTH Aachen University

Brief Summary

The purpose of this study is to determine whether additional pharmaceutical care for elderly patients (home-cared patients, nursing-home residents) has a positive impact on drug-related readmissions.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-04
• Study First Submitted: 2012-04-13
• Study First Submitted QC: 2012-04-13
• Study First Posted: 2012-04-17
• Status Verified: 2012-05
• Primary Completion: 2014-04
• Study Completion: 2014-04
• Last Update Submitted: 2015-10-29
• Last Update Posted: 2015-10-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 61

Inclusion Criteria

• patient 65 years old or older
• patient admitted to one of the project wards
• minimum hospitalization: 3 days
• written informed consent (patient or the legal representative)
• current medication of the patient at hospitalization

Exclusion Criteria

• patients included in this study previously

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intensified standard care	Pharmaceutical Care Service	Intensified standard care: traditional care by physician and nurse, additional pharmaceutical care by a pharmacist during hospitalization

Primary Outcome Measures

Name	Time	Method
Drug-related readmission	one year after discharge from the cooperating ward

Secondary Outcome Measures

Name	Time	Method
time for intervention	during hospital stay on cooperating wards (continuous data collection during routine ward rounds; hence, duration of data collection is dependent on individual hospital stay of each patient, up to one year) in the intervention group	time recording for pharmaceutical care service
number of changes in medication after discharge	one year
Adverse drug events	during hospital stay on cooperating wards(continuous data collection during routine ward rounds;hence,duration of data collection is dependent on individual hospital stay of each patient, up to 1 year) and 1 year after discharge from the cooperating ward
Number of prescribed potentially inappropriate medication (PRISCUS-criteria)	during hospital stay on cooperating wards(continuous data collection during routine ward rounds;hence,duration of data collection is dependent on individual hospital stay of each patient, up to 1 year) and 1 year after discharge from the cooperating ward	The PRISCUS list was developed in 2010 for the German market. Potentially inappropriate medications were judged as inappropriate by an expert panel using the Delphi technique. \[Holt et al., Dtsch Arztebl 2010\]
time to readmission	one year after discharge from the cooperating ward
Number of accepted recommendations in the intervention group	during hospital stay on cooperating wards (continuous data collection during routine ward rounds; hence, duration of data collection is dependent on individual hospital stay of each patient, up to one year) in the intervention group
drug-related problem	during hospital stay on cooperating wards (continuous data collection during routine ward rounds; hence, duration of data collection is dependent on individual hospital stay of each patient, up to one year) in the intervention group

Trial Locations

Locations (1)

University Hospital Aachen; 🇩🇪 Aachen, Germany