Effect of a trAnSitional Pharmacist Intervention in geRiatric Inpatients on Hospitals Visits After dischargE
- Conditions
- Drug-Related Side Effects and Adverse Reactions
- Interventions
- Other: Multifaceted clinical pharmacy intervention
- Registration Number
- NCT04617340
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Brief Summary
A randomized controlled trial will be performed in geriatric inpatients to investigate the impact of a multifaceted clinical pharmacy intervention on health related outcomes.
- Detailed Description
Since drug-related harm remains persistently prevalent in older adults, there is an urgent and unmet clinical need to optimize pharmacotherapy both during hospital stay and after discharge Therefore, we aim to perform a randomized controlled trial in geriatric inpatients to investigate the impact of a multifaceted clinical pharmacy intervention on health related outcomes. The primary objective is to reduce all-cause unplanned hospital visits in geriatric inpatients. Secondary objective are to optimize drug therapy in geriatric inpatients and improve their health; To empower and educate patients, caregivers,community pharmacists and physicians regarding drug regimen decisions to maximize therapy adherence and the understanding of the (de)prescribing process and to enhance healthy ageing; To optimize transitional care from the hospital to primary care.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 827
- Patients admitted to one of the study wards under supervision of a geriatrician
- A written informed consent by the patient or his/her representative
- Discharged from the hospital
- Admitted for a maximum of one day
- Unable to understand Dutch
- Being in a palliative stage as stated in their medical record with active withdrawal of drug therapy
- Patients being discharged to another ward within the same hospital or to another hospital
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Intervention group Multifaceted clinical pharmacy intervention The clinical pharmacist-collaborative service in the intervention group comprises six steps based on the clinical pharmacy intervention proposal of Van der Linden et al (Drugs Aging 2020). The first three steps focus on optimizing the drug therapy of geriatric inpatients. The remaining steps target a safe transition from the hospital to the community.
- Primary Outcome Measures
Name Time Method Time to all-cause unplanned hospital visit after discharge. up to six months after discharge An unplanned hospital visit is defined as an unplanned hospital admission or an emergency department visit
- Secondary Outcome Measures
Name Time Method Mortality Up to six months after discharge Death date
General practitioners contacts Up to six months after discharge Number of general practitioners contacts
Patient reported drug related problems Up to one month after discharge Number of drug related problems
Other types of hospital visits Up to six months after discharge Number of planned hospital admissions, number of emergency department visits, number of unplanned hospital admissions
Differences in pain Up to one month after discharge Numeric Rating Scale (NRS score) once a week (min 0 - max 10), a higher score indicating more pain
Medication adherence On admission and one month after discharge BAASIS tool
Cost-effectiveness Up to six months after discharge Healthcare related costs and Medicine productivity costs
Drug-related readmissions Up to six months after discharge Number of drug related readmissions
Fall incidents Up to one month after discharge Number of falls
Change in Quality of life on admission, one month after discharge and six months after discharge five-level version of the EuroQol five-dimensional (EQ5D) descriptive system (EQ-5D-5L) questionnaire. values will be tranformed using a value set to a score from 0 - 1 (a higher score indicating a better quality of life)
Medications On admission, at discharge and one month after discharge Number of medications
Potentially inappropriate medications On admission, at discharge and one month after discharge RASP tool
Trial Locations
- Locations (1)
University Hospitals Leuven
🇧🇪Leuven, Belgium