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Impact of Hospital Pharmacist Intervention on Medication Management in Dialysis Patients

Not Applicable
Not yet recruiting
Conditions
Renal Dialysis
Health Literacy Level
Kidney Disease, Chronic
Registration Number
NCT06692231
Lead Sponsor
Centre Hospitalier de Vichy
Brief Summary

The goal of this clinical trial is to learn if an intervention of a hospital pharmacist could help, dialysis patients managed his treatment. In a first time, the health literacy level will be assed.

The main questions it aims to answer are:

What is the impact of the clinical pharmacist intervention on the understanding level and management level of his treatment by the patient? Does the intervention of the pharmacist has an effect on the biologicals parameters of the patient? Researchers will compare a group with a pharmacist intervention VS a group without pharmacist intervention for dialysis patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
70
Inclusion Criteria
  • Patient over 18 years of age
  • On dialysis (peritoneal dialysis, hemodialysis) for at least 3 months
  • Prescription for at least 5 daily medications
  • Patient who has not received any pharmaceutical consultation from a hospital pharmacist as part of his or her treatment for chronic renal failure.
Exclusion Criteria
  • Patient does not speak and/or understand French
  • Patient's cognitive state does not permit an interview
  • Patient not autonomous in managing his or her daily medication (e.g.: patient in nursing home)
  • Patient refusal

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Level of understanding and treatment management12 months

Assessment of level of understanding and management of treatment using a survey based on the questionnaire validated by the French Health Authority (HAS).

In order to take better account of the diversity of treatments for dialysis patients, we will use an adaptation of this questionnaire describing more precisely the patient's knowledge of treatments related to phosphocalcic metabolism and potassium.

A score of 7 on this questionnaire means an excellent understanding of the treatment A score of 0 on this questionnaire means the poorest understanding of the treatment

Secondary Outcome Measures
NameTimeMethod
Phosphatemia evolution12 months

concentration of phosphate in blood plasma

Calcemia evolution12 months

concentration of calcium in blood plasma

PTH evolution12 months

concentration of PTH in blood plasma

Vitamine D evolution12 months

concentration of vitamine D in blood plasma

Quality of life12 months

Patients' quality of life will be assessed using the EQ-5D-5L tool. The EQ-5D descriptive system comprises five dimensions: mobility, self-care, usual activities, pain and discomfort, and anxiety and depression. Each dimension is describe by a five levels scale. (From 0 the worst outcome to 5 the best outcome). A visual analogue scale, where the patient rate is health form 0 to 100, complete this descriptive system.

Assessment of compliance with medication12 months

Call to the patient's usual pharmacy to check that medication retrieval is regular and get the pharmacist's opinion of the patient, by asking the following question: "Based on the last 6 months in your pharmacy's patient file, how would you rate the regularity of this patient's medication retrieval? "Good - Intermediate - Poor".

level of health literacy12 months

Literacy will be assessed measured using the French version of the Short Test of Functional Health Literacy in Adults (STOFHLA).

STOFHLA scale interpretation:

Score 0-16: Inability to read and interpret healthcare texts Score 17-22: Problem reading and interpreting healthcare texts Score 23-36: Can read and interpret most healthcare texts

Assessment of patient-reported compliance with medication12 months

The patient-reported compliance will be assed using the GIRERD questionnaire. This tool is made of 6 questions. A score of 0 mean a good compliance and a score ≥3 mean a bad compliance

Kalemia evolution12 months

concentration of potassium in blood plasma

Trial Locations

Locations (1)

Centre hospitalier de Vichy

🇫🇷

Vichy, France

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