Validation of a Record-based Frailty Assessment According to the Multidimensional Prognostic Index

Completed

• Conditions: Frail Elderly Syndrome
• Interventions: Other: No intervention.

• Registration Number: NCT03794674
• Lead Sponsor: University of Aarhus

Brief Summary

Background Various phenotype and cumulative frailty assessment tools have been developed and compared in research. For use in an in-hospital setting, a cumulative and graded frailty assessment method is preferred in order to identify subgroups of patients at risk of adverse events during discharge and transition to primary care. Comprehensive Geriatric Assessment (CGA) is the gold standard to assess frailty. Most medical wards have limited access to specialized geriatric team support capable of performing CGA. Thus in these wards there is a need for a CGA based instrument to identify the frail patients and to quantify the level of frailty. The Multidimensional Prognostic Index (MPI) is based on CGA and is a comprehensive cumulative deficit frailty assessment tool validated in a Danish geriatric department. MPI is fully applicable in the everyday clinical work and supplies useful information to clinicians. It can predict readmission and death, and it is well-suited to assess the degree of frailty. Enabling identification of patients at risk of adverse events facilitates targeting of the interventions in order to improve patient outcomes. The MPI is a bedside assessment. However, in observational record-based research the patient is not accessible for the researcher. To assess and identify hospitalized frail patients retrospectively for clinical research, a valid record-based frailty assessment method is needed. The aim of this study is to compare the accuracy of a record-based MPI assessment with a bedside performed MPI assessment in order to use the record-based MPI when access to bedside MPI is impossible.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2018-12
• Study Start: 2018-12-04
• Study First Submitted: 2018-12-21
• Study First Submitted QC: 2019-01-02
• Study First Posted: 2019-01-07
• Primary Completion: 2019-02-21
• Study Completion: 2019-02-22
• Last Update Submitted: 2019-10-07
• Last Update Posted: 2019-10-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

• Acutely admitted to one of the two medical departments listed below
• Aged 75 years or older
• Living within the municipality of Aarhus

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Exclusion Criteria

• Included in any other kind of follow-up schemes
• Already included in this study
• Declared terminally ill or undergoing palliative care at admission
• Admitted from one specific temporary nursing home with geriatric medical assistance (Vikærgården)
• Discharge or transfer to another department, including hospice
• The patient does not want to participate in the MPI-screening process

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
MPI test group	No intervention.	50 eligible patients. Frailty level independently assessed by two reviewers based on the medical records and assessed by one research assistant based on bedside testing.

Primary Outcome Measures

Name	Time	Method
Sumscore	1 day	The relative difference between the two measurements' sumscores calculated as an Intraclass Correlation Coefficient (ICC)

Trial Locations

Locations (1)

Aarhus University; 🇩🇰 Aarhus, Denmark