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Ottawa Hospital Research Institute

Ottawa Hospital Research Institute logo
🇨🇦Canada
Ownership
Private
Established
2001-01-01
Employees
5K
Market Cap
-
Website
http://www.ohri.ca

Clinical Trials

529

Active:27
Completed:275

Trial Phases

6 Phases

Early Phase 1:1
Phase 1:23
Phase 2:55
+3 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (402 trials with phase data)• Click on a phase to view related trials

Not Applicable
225 (56.0%)
Phase 4
60 (14.9%)
Phase 2
55 (13.7%)
Phase 3
38 (9.5%)
Phase 1
23 (5.7%)
Early Phase 1
1 (0.2%)

Mesenchymal Stromal Cell Therapy to Prevent Bronchopulmonary Dysplasia in Extreme Preterm Infants

Not Applicable
Not yet recruiting
Conditions
Bronchopulmonary Dysplasia (BPD)
ELGAN (22-28SA)
Interventions
Biological: Human Allogenic Umbilical Cord Mesenchymal Stromal Cells
Other: Sham procedure control
First Posted Date
2025-07-10
Last Posted Date
2025-07-10
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
168
Registration Number
NCT07058025
Locations
🇨🇦

Royal Alexandra Hospital/Stollery Children's Hospital, Edmonton, Alberta, Canada

🇨🇦

McMaster Children's Hospital, Hamilton, Ontario, Canada

🇨🇦

The Ottawa Hospital, Ottawa, Ontario, Canada

and more 5 locations

Lower Trapezius Tendon Transfer vs Partial Cuff Repair in Massive Rotator Cuff Tears

Not Applicable
Not yet recruiting
Conditions
Massive Rotator Cuff Tear
First Posted Date
2025-07-04
Last Posted Date
2025-07-04
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
60
Registration Number
NCT07051889
Locations
🇨🇦

The Ottawa Hospital, Ottawa, Ontario, Canada

Variability and Post-op AEs: Does Preoperative CardioPulmonary Variability Assessment Identify Risk of Postoperative Adverse Events Following Thoracic Surgery

Not yet recruiting
Conditions
Thoracic Cancer
Complication,Postoperative
First Posted Date
2025-06-11
Last Posted Date
2025-06-19
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
130
Registration Number
NCT07016022

Safe Effective Therapy With Low-Dose Glucocorticoid in ANCA-Associated Vasculitis (SAFE-LOW)

Phase 3
Not yet recruiting
Conditions
Granulomatosis With Polyangiitis
Microscopic Polyangiitis (MPA)
Interventions
First Posted Date
2025-05-21
Last Posted Date
2025-05-21
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
36
Registration Number
NCT06983821
Locations
🇨🇦

St-Joseph's Hospital, Hamilton, Ontario, Canada

🇨🇦

The Ottawa Hospital, Ottawa, Ontario, Canada

A Pilot Trial Comparing Full Dose Rivaroxaban to Prophylactic Dose Rivaroxaban in Patients With Superficial Vein Thrombosis in the Leg

Phase 2
Not yet recruiting
Conditions
SVT
Thrombosis
Superficial Vein Thrombosis
Interventions
Drug: Full dose rivaroxaban
Drug: Low dose rivaroxaban and placebo
First Posted Date
2025-05-11
Last Posted Date
2025-05-11
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
50
Registration Number
NCT06965998
Locations
🇨🇦

The Ottawa Hospital, Ottawa, Ontario, Canada

🇨🇦

Hopital Montfort, Ottawa, Ontario, Canada

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News

Tranexamic Acid Fails to Reduce Transfusions in Radical Cystectomy: TACT Trial

• A randomized, double-blind, placebo-controlled trial (TACT) assessed tranexamic acid (TXA) in patients undergoing radical cystectomy for bladder cancer. • The study found that TXA did not significantly reduce the need for red blood cell transfusions within 30 days post-surgery compared to placebo. • Secondary outcomes, including blood loss and thromboembolic events, also showed no significant differences between the TXA and placebo groups. • The findings suggest that routine use of TXA during open radical cystectomy for bladder cancer is not recommended.

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