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Clinical Trials/NCT00872313
NCT00872313
Completed
Not Applicable

Potential Risk Factors for Postpartum Psychosis

Nanjing Medical University1 site in 1 country4,000 target enrollmentFebruary 2009

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postpartum Period
Sponsor
Nanjing Medical University
Enrollment
4000
Locations
1
Primary Endpoint
Incidence of psychoses
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

A range of psychological disorders occur in women in the postpartum period. These include "the blues", which occurs in the first days after birth and which is very common and self-limiting; severe psychoses often associated with mania or bipolar illness, occurring in the first weeks after birth; and mild to moderate depression, occurring weeks to months after birth. Studies have been done focused on postpartum psychosis using a retrospective investigation, which gave only a limited material on the prevalence of psychological disorders in postpartum women. The investigators hypothesized that different pathways to psychosis function as the risk factors which may be overlapped, truly independent, mediating, or moderating, in new mothers who are at high risk and/or during the early period of delivery. In addition, the investigators purposed that the temporal sequence of biological, social and demographic variables are also the potential factors contributing to the development of postpartum psychosis.

Registry
clinicaltrials.gov
Start Date
February 2009
End Date
August 2012
Last Updated
12 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Nanjing Medical University
Responsible Party
Principal Investigator
Principal Investigator

Fu Zhou Wang

Dr

Nanjing Medical University

Eligibility Criteria

Inclusion Criteria

  • Pregnant women

Exclusion Criteria

  • Age \< 18 years or \> 50 years
  • Gestational age \< 32 weeks

Outcomes

Primary Outcomes

Incidence of psychoses

Time Frame: 3 months and 6 months postpartum

Secondary Outcomes

  • Antepartum economic level(One year before labor and delivery (recorded by antepartum communication))
  • Antepartum social status(One year before labor and delivery (recorded by antepartum communication))
  • Antepartum psychological level(1 day before birth)
  • Intrapartum complications(1 day after birth)
  • Baby characteristics(One minute, 5min, 15min after baby was born)
  • Maternal characteristics(One day after birth)
  • Medical caregiver characteristics(One day before and after the labor completion)
  • Parturient family characteristics(One week before labor and delivery, recorded by investigators through patients' antepartum communication)
  • Intrapartum medical procedures(One day after birth)

Study Sites (1)

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