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Clinical Trials/NCT06553300
NCT06553300
Recruiting
Not Applicable

Auto Transplantation of Wisdom Teeth With or Without Platelet Rich Fibrin for Replacement of Non-Restorable Posterior Teeth.

Cleveland Dental Institute1 site in 1 country20 target enrollmentJanuary 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Autotransplantation of Wisdom Teeth
Sponsor
Cleveland Dental Institute
Enrollment
20
Locations
1
Primary Endpoint
Radiographic success
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

Autotransplantation emerges as a viable alternative to tooth extraction and prosthetic restoration when conventional endodontic treatments are unfeasible or contraindicated. The success of autotransplantation is influenced by diverse factors, including root development stage, tooth morphology, surgical technique, extraoral duration, recipient socket shape, recipient bed vascularity, and periodontal ligament cell vitality. Preserving periodontal ligament quality and achieving tissue adaptation are pivotal for successful tooth transplantation. Successful donor tooth replacement is influenced by variables like fitting attempts, alveolus-root distance, extra-alveolar time, surgical skill, and extraction trauma intensity.

Registry
clinicaltrials.gov
Start Date
January 1, 2024
End Date
March 31, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Cleveland Dental Institute
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • male and female
  • aged between 20 and 50 years
  • devoid of systemic ailments
  • complying with the study procedures
  • holding an Anesthesiologists classification of 1 or 2
  • possessing mandibular or maxillary immature wisdom teeth

Exclusion Criteria

  • systemic diseases that might impede the healing process
  • Patients with pacemakers
  • Individuals harboring allergies to medications or antibiotics
  • active smokers
  • patients afflicted with periodontal diseases

Outcomes

Primary Outcomes

Radiographic success

Time Frame: one year

The success of auto-transplanted immature third molars with and without Platelet-Rich Fibrin will be assessed over a year period.

Study Sites (1)

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