Autogenous Tooth Transplantation of Canines - A Prospective Study on the Clinical Benefit of Adjunctive Antibiosis
- Conditions
- Autogenous tooth transplantation
- Registration Number
- DRKS00034011
- Lead Sponsor
- MU Klinikum - Poliklinik für Zahnerhaltung und Parodontologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 67
1.)Indication for autogenous transplantation of a displaced canine. This is given in cases of definite retention of the tooth, possibly after exhausting orthodontic treatment options. Clinical or radiological findings can include: total displacement with resorption of adjacent teeth, mechanical retention (for example, pronounced root hooks or impaction), delay of the physiological eruption time by more than two years, unsuccessful attempt at integration through exposure and bracketing (19–21).
2.)Patient consent (and parental consent for minors)
3.)Acceptable oral hygiene (Gingiva, plaque, and calculus index = 1)
4.)Patient age of at least 11 years
1.)Psychomotor retardation with inability to consent
2.)Severe systemic illness (congenital/acquired), e.g., syndromal diseases or similar, unstable metabolic disorders, etc.
3.)Immunodeficiency (congenital/acquired/medication-associated)
4.)Current or past malignancy
5.)Chromosomal aberrations
6.)Severe coagulation disorders
7.)Bone diseases or ossification disorders
8.)Alcohol, narcotic, or medication abuse
9.)Heavy nicotine abuse (consumption of > 20 cigarettes/day)
10.)Use of cortisone, bisphosphonate, or denosumab derivatives
11.)Lack of compliance
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Success rate of canine transplants two years postoperatively (assessed according to various clinical and radiological parameters)
- Secondary Outcome Measures
Name Time Method Survival rate of the canine transplants two years postoperatively