Auto Transplantation of Wisdom Teeth

Not Applicable

Recruiting

• Conditions: Patelet Rich Fibrin; Autotransplantation of Wisdom Teeth
• Interventions: Procedure: Autotransplantation with PRF; Procedure: Autotransplatation Only

• Registration Number: NCT06553300
• Lead Sponsor: Cleveland Dental Institute

Brief Summary

Autotransplantation emerges as a viable alternative to tooth extraction and prosthetic restoration when conventional endodontic treatments are unfeasible or contraindicated. The success of autotransplantation is influenced by diverse factors, including root development stage, tooth morphology, surgical technique, extraoral duration, recipient socket shape, recipient bed vascularity, and periodontal ligament cell vitality. Preserving periodontal ligament quality and achieving tissue adaptation are pivotal for successful tooth transplantation. Successful donor tooth replacement is influenced by variables like fitting attempts, alveolus-root distance, extra-alveolar time, surgical skill, and extraction trauma intensity.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-01
• Status Verified: 2024-07
• Study First Submitted: 2024-07-29
• Study First Submitted QC: 2024-08-09
• Last Update Submitted: 2024-08-09
• Study First Posted: 2024-08-14
• Last Update Posted: 2024-08-14
• Primary Completion: 2024-10-31
• Study Completion: 2025-03-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• male and female
• aged between 20 and 50 years
• devoid of systemic ailments
• complying with the study procedures
• holding an Anesthesiologists classification of 1 or 2
• possessing mandibular or maxillary immature wisdom teeth

Exclusion Criteria

• systemic diseases that might impede the healing process
• Patients with pacemakers
• Individuals harboring allergies to medications or antibiotics
• active smokers
• patients afflicted with periodontal diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Autotransplantation with PRF	Autotransplantation with PRF	-
Autotrasplantation only	Autotransplatation Only	-

Primary Outcome Measures

Name	Time	Method
Radiographic success	one year	The success of auto-transplanted immature third molars with and without Platelet-Rich Fibrin will be assessed over a year period.

Trial Locations

Locations (1)

Cleveland Dental Institute; 🇺🇸 Cleveland, Ohio, United States