Extracted tooth roots as autogenous transplants for combined horizontal-/ vertical alveolar ridge augmentation. A controlled clinical study.

Not Applicable

• Conditions: K08.1; K08.2; Loss of teeth due to accident, extraction or local periodontal disease; Atrophy of edentulous alveolar ridge

• Registration Number: DRKS00016717
• Lead Sponsor: Poliklinik für Zahnärztliche Chirurgie und ImplantologieZentrum für Zahn-, Mund- und Kieferheilkunde (Carolinum)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-02-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

Insufficient bone ridge width and height at the recipient site for implant placement
- extraction of non-retainable tooth/ teeth (refers to groups receiving autogenous tooth roots)
- Healthy oral mucosa, at least 3 mm keratinized mucosa

Exclusion Criteria

- Inflammatory and autoimmune disease of oral cavity
- Uncontrolled HbA1c (> 7%) in diabetes patients
- History of malignancy requiring chemotherapy or radiotherapy within the past five years
- Concurrent or previous radiotherapy of head area
- Concurrent or previous immunosuppressant, bisphosphonate or high dose corticosteroid therapy
- Smokers
- Pregnancy or lactating women

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical width and height of the alveolar ridge at 26 weeks (calibrated caliper/ probe)

Secondary Outcome Measures

Name	Time	Method
-Soft tissue healing at day 10, week 4, 13, 26, 26 +10 days, 26 + 10 weeks and 26 + 26 weeks (arbitrary scale)<br>-Implant Survival (yes/ no)<br>-Peri-implant indices (i.e. plaque index - PI, bleeding on probing - BOP, probing pocket depth – PD, mucosal recession - MR) at 26 + 10 weeks and 26 + 26 weeks <br>