The Utility of Oxygen Insufflation During Flexible Fiberoptic Bronchoscope-guided Intubation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Velocity of PaO2 decrease
研究概览
简要总结
This study investigate the utility of continuous oxygen insufflation during fiberoptic bronchoscope-guided intubation.
One group receives oxygen via suction channel of fiberoptic bronchoscope during intubation.
The other group does not receive oxygen during fiberoptic bronchoscope-guided intubation.
Then, the velocity of deoxygenation difference of PaO2(baseline
详细描述
Fiberoptic bronchoscope-guided intubation is a gold standard for intubation of a patient with anticipating difficult airway. This technique takes several minutes without oxygen supply, which results in hypoxia when it prolonged. If continuous supply of oxygen during procedure improve the oxygenation, we can reduce the risk of hypoxemia and increase the safety margin during procedure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who have surgery under general oral endotracheal anesthesia with invasive arterial blood pressure monitoring
排除标准
- •history of lung disease
- •abnormality in chest x-ray
- •anticipating difficult intubation
- •pregnant women
- •who is unable to understand and agree the consent form
研究组 & 干预措施
Oxygen
Oxygen is supplied through suction port in bronchoscope during bronchoscope-guided intubation.
干预措施: Oxygen (Drug)
结局指标
主要结局
Velocity of PaO2 decrease
时间窗: from mask removal to 1st manual ventilation after intubation, up to 5 minute
After administration of anesthetic agents and manual ventilation of 5 minutes, arterial blood sampling is collected. Then bronchoscope-guided intubation performed and arterial blood sample is collected immediately after the intubation completed. Time for intubation (between 1st and 2nd blood sample) is recorded. The difference of PaO2(before \& after intubation) is divided by the time taking for intubation.
次要结局
- visual field(throughout the intubation with bronchoscope, upto 5 minute)
- success of intubation(300 sec after the beginning of intubation)
- pH(1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute)
- PaO2(1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute)
- PaCO2(1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute)