EUCTR2009-016907-41-DE
Active, not recruiting
Not Applicable
Investigation of nociceptive and antinociceptive mechanisms under anesthesia using fMRI, EEG and noxious reflexes - Nociceptive mechanisms under anesthesia
ConditionsThis is a CT including only healthy volunteers. The aim of the study is to investigate the effect of a commonly used anesthetic drug in clinical concentrations on nociceptive and antinociceptive mechanisms.Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- This is a CT including only healthy volunteers. The aim of the study is to investigate the effect of a commonly used anesthetic drug in clinical concentrations on nociceptive and antinociceptive mechanisms.
- Sponsor
- Charité, Universitätsmedizin Berlin
- Status
- Active, not recruiting
- Last Updated
- 12 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Informed consent
- •\- Age between 18\-60 years
- •\- No participation in other studies
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 12
- •F.1\.3 Elderly (\>\=65 years) no
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •\- Any light or severe disease
- •\- Especially, even in the lightest cases: infection of the respiratory system, muscular diseases, diseases of the CNS, chronic pain diseases, drug or medication abuse
- •\- Claustrophobia
- •\- Conditions with an increased risk of aspiration, expecially adipositas (BMI\>\=30kg/m²)
- •\- pregnancy or lactation
- •\- history or family history of malignant hyperthermia
- •\- history or family history of allergic reactions against propofol, remifentanil, soja, latex
- •\- Placement in an institution on official authorities order or judicial order
- •\- implants, especially pacemakers, cardioverters, cochlea implants, insulin pumps, nerve stimulators, vascular clips, cava filters, metal splints, screws, wires, plates
- •\- extensive or looped tattoos, piercings, other ferromagnetic ornaments which cannot be removed
Outcomes
Primary Outcomes
Not specified
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