It is intended to investigate the mechanisms of the processing of pain unter anesthesia in healthy volunteers by using the methods fMRI, EEG and noxious reflexes.
- Conditions
- This is a CT including only healthy volunteers. The aim of the study is to investigate the effect of a commonly used anesthetic drug in clinical concentrations on nociceptive and antinociceptive mechanisms.Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
- Registration Number
- EUCTR2009-016907-41-DE
- Lead Sponsor
- Charité, Universitätsmedizin Berlin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
- Informed consent
- Age between 18-60 years
- No participation in other studies
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 12
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
- Any light or severe disease
- Especially, even in the lightest cases: infection of the respiratory system, muscular diseases, diseases of the CNS, chronic pain diseases, drug or medication abuse
- Claustrophobia
- Conditions with an increased risk of aspiration, expecially adipositas (BMI>=30kg/m²)
- pregnancy or lactation
- history or family history of malignant hyperthermia
- history or family history of allergic reactions against propofol, remifentanil, soja, latex
- Placement in an institution on official authorities order or judicial order
- implants, especially pacemakers, cardioverters, cochlea implants, insulin pumps, nerve stimulators, vascular clips, cava filters, metal splints, screws, wires, plates
- extensive or looped tattoos, piercings, other ferromagnetic ornaments which cannot be removed
- lack of consent to the storage and transmission of data within the scope of the clinical trial
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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