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临床试验/NCT07351552
NCT07351552尚未招募不适用

The Effect of Frailty in Geriatric Patients on Hypotension Observed After Anesthesia Induction

Selcuk University0 个研究点目标入组 80 人开始时间: 2026年1月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
80

研究概览

简要总结

Frailty is defined as a state of weakness resulting from a decrease in physiological reserves due to physiological changes, diseases, and/or malnutrition associated with advancing age. Frail older adults face increased mortality, morbidity, and healthcare costs when exposed to stressors, making this issue increasingly important. The FRAIL Scale, developed by Morley et al. , is a 5-item measure that assesses frailty. The FRAIL Scale has been validated in many countries and has been proven to be an effective method for detecting frailty. This scale assesses the patient's fatigue, resistance, mobility, weight loss, and other diseases. In the 5-item FRAIL scale, patients receive 0 or 1 point based on their answers, and a total of 0 points is considered non-frail, 1-2 points is considered pre-frail, and >2 points is considered frail.

Frailty is associated with a higher risk of postoperative complications. Rothenberg and colleagues reported in a study involving more than 400,000 patients that frailty doubles the risk of postoperative complications .

Hypotension following anesthesia induction is a common complication in geriatric patients. Decreased cardiopulmonary reserve with age leads to an exaggerated drop in blood pressure during induction .

In this study, the investigators aimed to determine the effect of frailty level in geriatric patients on hypotension observed after anesthesia induction.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Prospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who do not have difficulty communicating,
  • have good cognitive function,
  • scheduled for surgery under general anesthesia

排除标准

  • Patients admitted for surgery in emergency situations
  • Patients with active malignancy
  • Patients with physical disabilities and impairments (limb amputations, stroke sequelae, unable to speak, hearing problems)
  • Patients with acute infections
  • Patients with acute illnesses (decompensated congestive heart failure, recent myocardial infarction/stroke, COPD exacerbation)
  • Patients who have been hospitalized or undergone surgery within the last month
  • Patients with advanced dementia
  • Patients who are unable to provide a medical history or cooperate

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

EMİNE ASLANLAR

associated professor

Selcuk University

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