The comparison of cervical vestibular evoked myogenic potential (cVEMP) between definite Meniere’s disease(MD) patient and normal subjects

Phase 1

• Conditions: To assess saccular function in definite Meniere’s patients by cervical vestibular evoked myogenic potential (cVEMP); cVEMP meniere disease

• Registration Number: TCTR20180521001
• Lead Sponsor: reserach affair faculty of medicine chulalongko

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-05-21
• Study Completion: 2018-07-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Control group
1.no underlying diseade or dizzy or vetigo symptoms
2.E.N.T examination was noral
3 normal hearing in audiogram
experimental group
Unilateral MD patients as the clinical criteria AAO-HNS 2015 which include
A. Two or more spontaneous episodes of vertigo, each lasting
20 minutes to 12 hours(
B. Audiometrically documented low to medium frequency
sensorineural hearing loss in one ear, defining the affected ear
on at least one occasion before, during or after one of the episodesof vertigo
C. Fluctuating aural symptoms (hearing, tinnitus or fullness) in the
affected ear(
D. Not better accounted for by another vestibular diagnosis

Exclusion Criteria

1 patient with middle ear and external ear disease
2.head and neck surgery or problem with c spine and neck muscle which impacted ROM of neck eg, torticolis
3.using relaxant medication eg, mydocalm ,ketamine, Mydocalm anticonvulsant eg Ketamine, Prochlorperazine, Haloperidol, Chlorpromazine
4.pregnancy or on cardiacpacemaker

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
p13 latency,n23 latency,p13-n23 amplitude ,amplitude asymmetry ratio After enrollment patient cVEMP measurement

Secondary Outcome Measures

Name	Time	Method
no no no