Cervical Vestibular Evoked Myogenic Potentials in Recurrent and Persistant Benign Paroxysmal Positional Vertigo

Recruiting

• Conditions: Benign Paroxysmal Positional Vertigo
• Interventions: Device: Cervical VEMP testing

• Registration Number: NCT05922774
• Lead Sponsor: Haseki Training and Research Hospital

Brief Summary

The goal of this observational study is to compare the cervical vestibular evoked myogenic potentials in recurrent/persistant BPPV and nonrecurrent BPPV. Recurrent/persistant BPPV is considered as the patients who require more than one repositioning manuever for the resolution of symptoms and the recurrent cases in the first three months after the diagnosis.

The main question\[s\] it aims to answer are:

* Is there any difference between the cVEMP findings of diseased ears of recurrent and nonrecurrent BPPV cases?

* Is there any difference between the cVEMP findings of diseased ears and healthy ears of BPPV patients

* Is there any difference between the cVEMP findings of healthy ears of recurrent and nonrecurrent BPPV cases and healthy controls?

Patients with VNG confirmed BPPV will be recruited and CVEMP test will be performed before the therapeutic manuevers.

Control visits will be scheduled on the 7th day after the therateutic menuevers are performed.

Patients will be followed-up for 4 weeks after the resolution of symptoms. Researchers will compare recurrent (Group 1), nonrecurrent (group 2) BPPV patients and healthy controls (Group 3) to see if there is any difference between the cVEMP findings of two groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-06-19
• Study First Submitted: 2023-06-19
• Study First Submitted QC: 2023-06-19
• Study First Posted: 2023-06-28
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-18
• Last Update Posted: 2023-07-20
• Primary Completion: 2023-12-25
• Study Completion: 2024-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Patients admitted to ENT clinic with unilateral posterior or lateral canal BPPV for the first time

Exclusion Criteria

• patients with bilateral BPPV
• patients with recurrent or resistant BPPV
• patients with spontaneous nystagmus
• vestibular or neurologic disorders other than BPPV
• patients who use medication which may affect the vestibular system or muscle tone
• cervical muscle disorders and ocular pathologies which may affect the VEMP results

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 1	Cervical VEMP testing	Patients with recurrent BPPV
Group 3	Cervical VEMP testing	Healthy controls
Group 2	Cervical VEMP testing	Patients with non recurrent BPPV

Primary Outcome Measures

Name	Time	Method
The comparison of cVEMP findings in normal controls and BPPV patients with nonrecurrent and recurrent BPPV symptoms after 4 week follow-up.	13 weeks	Patients with VNG confirmed BPPV will be recruited and CVEMP test will be performed before the therapeutic manuevers.; Control visits will be scheduled on the 7th day after the therapeutic menuevers are performed.; Patients will be followed-up for 4 weeks after the resolution of symptoms. Researchers will compare recurrent (Group 1), nonrecurrent (group 2) BPPV patients and healthy controls (Group 3) to see if there is any difference between the cVEMP findings of these groups.

Trial Locations

Locations (1)

Haseki Training and Research Hospital; 🇹🇷 İstanbul, Turkey