Effect of PRF as a complementary therapy in the treatment of periodontal disease

Not Applicable

• Conditions: Periodontal Pocket; H02.163.876.623

• Registration Number: RBR-52h647m
• Lead Sponsor: Faculdade de Odontologia da Universidade Federal de Uberlândia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-03-02
• Last Update Posted: 29 May 2023
• Study Completion: 2024-12-30

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with Stage III Periodontitis, with 5 mm or more of interproximal attachment loss or radiographic bone loss extending to the apical half or third of the root; may have vertical bone loss of up to 3 mm; grade II or III furcation lesions and moderate ridge defect; direct evidence of non-progression of attachment loss for 5 years or indirect evidence of bone loss/year up to 0.25 mm; patients with large accumulation of biofilm but little periodontal destruction; minimum of 20 teeth present and presence of two pairs of contralateral teeth with proximal periodontal sites presenting probing depth and clinical attachment level = 5 mm

Exclusion Criteria

Underage patients; patients who do not agree with the informed consent and do not sign it; tooth loss of 5 or more teeth due to periodontitis; positive history of antibiotic therapy in the last six months; positive history of nonsurgical periodontal therapy in the last six months; systemic involvement that may interfere with disease progression or response to treatment; need for antibiotic prophylaxis for routine dental procedures; use of anti-inflammatory drugs for a long period of time; smoking; pregnancy

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the plaque index on dental surfaces, which will be verified by the percentage of tooth surfaces with plaque deposits stained with evidencing solution and it is expected to find a reduction in this plaque index;To evaluate the pocket depth on probing, which will be verified using a periodontal probe, after 90 days of non-surgical periodontal therapy, it is expected to find a reduction in this probing, with an expected depth equal to or less than 3 mm

Secondary Outcome Measures

Name	Time	Method
To assess the presence of bleeding on probing, which will be verified at the time of probing with the use of the periodontal probe, it is expected that, after 90 days of non-surgical periodontal therapy, there will be no bleeding on probing