DLapheresis-mediated Endothelial activation Therapy to Severe-Peripheral Artery Disease study(LETS-PAD study)
Not Applicable
- Conditions
- conventional therapy-resistant peripheral artery disease (PAD)without hypercholesterolemia
- Registration Number
- JPRN-jRCTs032180100
- Lead Sponsor
- Toya Yoshiyuki
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 35
Inclusion Criteria
(1)age between 20 and 80
(2)patients diagnosed as peripheral artery disease
(3)Fontaine classification >=IIB
(4)ankle brachial pressure index <0.7
(5)serum total cholesterol<=220mg/dl and LDL cholesterol<=140mg/dl
(6)PAD refractory to conventional therapy such as percutaneous transluminal angioplasty or bypass graft surgery
(7)PAD resistant to the ameliorations of atherosclerotic risk factors including medication
(8)patients with written informed consent
Exclusion Criteria
(1)uncontrolled diabetes despite insulin therapy
(2)severe hepatic disorders
(3)inevitable use of ACE inhibitors during the treatment period
(4)ineligible patients judged by physicians
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method