Endothelial progenitor cells mobilization induced by atorvastatin in patients with chronic coronaric disease (stable angina) treated with revascularization with antibody antiCD34 covered stent - ND
- Conditions
- MedDRA version: 6.1Level: PTClassification code 10011078coronaric chronic disease
- Registration Number
- EUCTR2007-002519-22-IT
- Lead Sponsor
- OSPEDALE POLICLINICO S. MATTEO
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
age 18-75 years; stable angina pectoris or silent ischemia, documented coronaropaty
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
current or recent statine therapy, ASA or ticlopidine/clopidogrel allergy, IMA (< 3 months), severe trauma, epatic, renal, ematologic disease, neoplasm, pregnancy,...
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: to evaluate the mobilizing endothelial effect of atorvastatin 10 mg and 80 mg induced by four treatment weeks in patients with PCI;Secondary Objective: to define functional characters (clonogenic and angiogenetic)of atorvastatin mobilized endothelial cells; to verify the duration of this mobilizating effect; ...;Primary end point(s): mobilizing endothelial effect of atorvastatin 10 mg and 80 mg induced by four treatment weeks in patients with PCI
- Secondary Outcome Measures
Name Time Method