Enabling Microbiomics- Driven Personalized Nutrition (EMPOWER)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Inflammatory Bowel Disease (IBD)
- Sponsor
- Mayo Clinic
- Enrollment
- 4001
- Locations
- 1
- Primary Endpoint
- To Correlate Differences in Diet and Microbiome with Different GI Symptoms and Disease States
- Status
- Enrolling By Invitation
- Last Updated
- 10 months ago
Overview
Brief Summary
The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions.
The main question investigators aim to answer is:
Are host genetics, diet, and microbiome all important determinants of GI disorders, and how their relative contribution varies among individuals and populations.
Investigators
Purna C. Kashyap, MBBS
Principal Investigator
Mayo Clinic
Eligibility Criteria
Inclusion Criteria
- •Age greater than or equal to 18 years
- •Gastrointestinal patients with or without genomic sequencing results available for the following cohorts:
- •Inflammatory Bowel Disease (IBD)
- •Irritable Bowel Syndrome (IBS)
- •Crohn's Disease
- •Celiac Disease
- •Constipation
- •Healthy age and sex matched controls with or without genomic sequencing results available
- •o Control is defined as patients without gastrointestinal disease or no symptoms at time of sampling
- •Able to provide written, informed consent
Exclusion Criteria
- •Patients with cognitive impairment
- •Active use of antibiotics at the time of stool collection
Outcomes
Primary Outcomes
To Correlate Differences in Diet and Microbiome with Different GI Symptoms and Disease States
Time Frame: From enrollment through study completion, an average of 1 year.
Investigators will prospectively follow the clinical course of the patients throughout the duration of the study. Patient health outcomes will be documented from their medical record while the study is actively enrolling or undergoing data analysis.