Comparing efficacy of different preparations of Tranexamic Acid in the management of melasma
- Conditions
- Health Condition 1: L811- Chloasma
- Registration Number
- CTRI/2023/10/058614
- Lead Sponsor
- Ashutosh Trivedi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
All adult patients diagnosed with facial melasma
Children < 18 years of age, pregnant or nursing women or women planning pregnancy during the duration of trial.
Patients with Extra - facial melasma
Patient unwilling to give consent to be part of trial.
Current use of oral or injectable contraceptives, hormone replacement therapy, blood thinning medications, photosensitizing drugs or drugs known to cause hyperpigmentation of skin.
Current or previous use of any medical treatment (topical or oral) or cosmetic procedure (chemical peel, Laser, Dermabrasion) for melasma within 9 months of study enrollment.
History of thromboembolic disease such as deep vein thrombosis (DVT), >2 spontaneous abortions, pulmonary embolism or cerebral thrombosis, stroke or subarachnoid haemorrhage.
Family history of thromboembolic disease.
Smoking, tobacco use.
Hypersensitivity to tranexamic acid or sunscreen ingredients.
Abnormal bleeding profile (PT INR, Bleeding Time, Clotting Time).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method