COMPARISON OF TWO DRUGS IN THE TREATMENT OF ORAL LICHEN PLANUS
Phase 3
- Conditions
- Health Condition 1: L438- Other lichen planus
- Registration Number
- CTRI/2023/03/050453
- Lead Sponsor
- OT APPLICABLE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Healthy adults aged between 18 to 60 years.
2.Symptomatic patients having only Oral involvement of Lichen Planus which is biopsy proven and has not responded to any topical therapy for 3 months.(ODSS score >30)
Exclusion Criteria
1.Patients having extraoral involvement of Lichen Planus and erosive type of Lichen Planus
2.Patients with uncontrolled or severe hypertension, diabetes mellitus
3.Patients with active or recurrent infections, severe respiratory, renal, hepatic or heart disease
4.Patients with underlying endocrine or hematopoietic disorders
5.Patients who have a habit of tobacco chewing, beetle nut chewing and smoking.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Efficacy of Oral Cyclosporine vs Oral Steroid in the treatment of Oral Lichen Planus.Timepoint: At baseline,a monthly follow up of the patient for three months ,followed by 2 monthly visits for the next 6 months.
- Secondary Outcome Measures
Name Time Method Safety of Oral Cyclosporine vs Oral Steroid in the treatment of Oral Lichen PlanusTimepoint: At the end of follow up,that is at 9 months.