Role of Low Inferior Mesenteric Artery Ligation During Laparoscopic Surgery for Rectosigmoid Cancer

Completed

• Conditions: Rectosigmoid Adenocarcinoma
• Interventions: Procedure: Laparoscopic colorectal resection

• Registration Number: NCT03557528
• Lead Sponsor: University of Roma La Sapienza

Brief Summary

During sigmoid or rectal cancer surgery, dissection of lymphnodes at the origin of inferior mesenteric artery is mandatory. Nevertheless, ligation of the origin of IMA should compromise blood supply to left colon and affect anastomosis. The aim of this retrospective evaluation is to compare high and low IMA ligation with preservation of LCA, with or without skeletonization of the origin of IMA in laparoscopic colorectal resection.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-01
• Primary Completion: 2016-12-31
• Study Completion: 2017-04-30
• Status Verified: 2018-06
• Study First Submitted: 2018-06-04
• Study First Submitted QC: 2018-06-04
• Last Update Submitted: 2018-06-04
• Study First Posted: 2018-06-15
• Last Update Posted: 2018-06-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• stage I-III carcinoma

Exclusion Criteria

• stage IV
• Urgent resection
• conversion to open surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 1	Laparoscopic colorectal resection	High Ligation of Inferior mesenteric artery
Group 2	Laparoscopic colorectal resection	Low ligation of inferior mesenteric artery with skeletonization at its origin

Primary Outcome Measures

Name	Time	Method
effectivenes of lymphnode dissection	3 years	number of dissected lymphnodes

Secondary Outcome Measures

Name	Time	Method
complication	3 years	incidence of anasthomotic leaks

Trial Locations

Locations (1)

Policlinico Umberto I; 🇮🇹 Roma, Italy