Evaluation of Placental Transfusion Techniques in Prevention of Prematurity Related Complications

Not Applicable

Not yet recruiting

• Conditions: Premature; Placental Transfusion

• Registration Number: NCT06812507
• Lead Sponsor: Alexandria University

Brief Summary

The objective of this study is to evaluate the general course and prognosis associated with different methods of placental transfusion (Intact umbilical cord milking, cut- umbilical cord milking and delayed cord clamping) in premature neonates over the first days of life

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-02
• Study First Submitted: 2025-02-03
• Study First Submitted QC: 2025-02-03
• Last Update Submitted: 2025-02-03
• Study First Posted: 2025-02-06
• Last Update Posted: 2025-02-06
• Study Start: 2025-02-10
• Primary Completion: 2025-07-28
• Study Completion: 2025-08-28

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

Premature neonates ≤ 32 weeks gestational age regardless birth weight who will be admitted to neonatal intensive care unit in the first day of life

Exclusion criteria:

Exclusion Criteria

Patient with any of the following will be excluded:

1. Preterm babies >32 weeks

2. Major congenital anomalies (complex cyanotic heart disease, major central nervous system anomalies).

3. Evidence of head trauma causing major intracranial hemorrhage.

4. Concern for abruptions, placenta previa or retroplacental hematoma. 6. Cord accident, or avulsion at the time of delivery. 7. Refusal to perform the intervention by the obstetrician

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Hemoglobin level	on admission (In first day after birth),as well as, at end of first , second and third weeks of lives	hemoglobin level will be measured in gram/dl