Detection of Pre-Diabetes in Overweight and Obese Children and Adolescents in Assiut Governorate
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 主要终点
- Prevalence of Pre-Diabetes in Overweight and Obese children and adolescents in Assiut governorate
研究概览
简要总结
Descriptive cross section study To detect prediabetes in overweight and obese children and adolescents in Assiut Governorate and to find out the possible risk factors.
详细描述
Childhood obesity has reached epidemic levels in developed as well as in developing countries, Overweight and obesity in childhood have significant impact on both physical and psychological health.
Childhood obesity has been linked to numerous medical conditions. These conditions include : fatty liver disease, sleep apnea, Type 2 diabetes, asthma, cardiovascular disease, high cholesterol, cholelithiasis (gallstones), glucose intolerance and insulin resistance, etc.
Obesity is associated with Prediabetes , a significant risk factor for development of type 2 diabetes mellitus T2DM and its accompanying complications.
In some populations, type 2 diabetes is now the dominant form of diabetes in children and adolescents.
Prediabetes is defined by a fasting glucose level of 100 to 125 mg/dL , glycated hemoglobin level (HbA1C) of 5.7% to 6.4% , or a glucose level of 140 to 199 mg/dL measured 2 hours after a 75-g oral glucose load. approximately 10% of people with prediabetes progress to having diabetes each year.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 10 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Both sexes , aged (10-18) years.
- •Body mass index calculated as weight in Kg/(height in meters)2 :
- •Over weight > 85% percentile
- •Obese > 95% percentile " On Egyptian growth chart "
排除标准
- •• Children and adolescents with type 2 diabetes mellitus.
- •Children and adolescents with drug history affecting blood glucose level as corticosteroids.
- •Children and adolescents with any condition affecting blood glucose level as Cushing disease.
结局指标
主要结局
Prevalence of Pre-Diabetes in Overweight and Obese children and adolescents in Assiut governorate
时间窗: Baseline
determine the prevalence of prediabetes in overweight and obese children and adolescents in Assiut Governorate and to find out the possible risk factors through many investigations as HbA1c , Fasting blood glucose level , Lipid profile in 150 obese children.
次要结局
未报告次要终点
研究者
Mahmoud Bakr Gaber
Principal Investigator
Assiut University