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Efficacy and safety of electroacupuncture plus Suanzaoren decoction for insomnia following stroke: a randomized controlled trial

Phase 1
Conditions
insomnia following stroke
Registration Number
ITMCTR2000003167
Lead Sponsor
Yichang Hospital of Traditional Chinese Medicine, Clinical Medical College of Traditional Chinese Medicine, China Three Gorges University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Aged 18–70 years, either sex;
2. Unilateral hemispheric stroke;
3. Fulfilling the diagnostic criteria of insomnia according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition;
4. Right handedness.

Exclusion Criteria

1. Insomnia before stroke or caused by poor sleeping conditions;
2. Diagnoses of other sleep disorders such as narcolepsy, obstructive sleep apnoea syndrome or rest-less legs syndrome;
3. Neurological or psychiatric diseases;
4. Patients associated with severe diabetes, hypertension, severe liver, kidney or thyroid dysfunction, and severe cardiac insufficiency;
5. Inability to read, understand and complete the forms or use the rating scales;
6. The presence of implants that could interfere with EA or a history of hypersensitivity to EA;
7. Having received Traditional Chinese Medicine in the past 1 months;
8. Having participated in other trials;
9. Taking sleep-affecting diet or medication;
10. Pregnant or preparing for pregnancy.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pittsburgh Sleep Quality Index;Polysomnography;
Secondary Outcome Measures
NameTimeMethod
Insomnia Severing Index;National Institutes of Health Stroke Scale;nocturnal concentration of melatonin;Hospital Anxiety and Depression Scale;Magnetic Resonance Imaging brain scanning;functional magnetic resonance imaging;
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