Adverse effect of chlorhexidine mouth rinse in patients undergoing orthodontic treatment
Phase 4
- Registration Number
- CTRI/2023/12/060600
- Lead Sponsor
- Department of Orthodontics and Dentofacial Orthopedics
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
subjects with included age groups for fixed orthodontic treatment.
with permanent dentition and no history of previous orthodontic treatment
Exclusion Criteria
subjects with genetic syndrome and other debilitating diseases
subjects with amalgam fillings and other metal restorations
subjects with mucosal lesions anywhere in the oral cavity
subjects allergic to artificial jewellery
smokers, alcoholics and habit of tobacco chewing
Study & Design
- Study Type
- PMS
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method salivary metal ions levels <br/ ><br>8-OHdG levelsTimepoint: T0- baseline <br/ ><br>T1- 2 weeks <br/ ><br>T2-6 weeks <br/ ><br>T3- 12 weeks <br/ ><br>
- Secondary Outcome Measures
Name Time Method Plaque index <br/ ><br>gingival index <br/ ><br>Bleeding on Probing <br/ ><br>calculus indexTimepoint: T0- baseline <br/ ><br>T1- 2 weeks <br/ ><br>T2-6 weeks <br/ ><br>T3- 12 weeks <br/ ><br>