Effects of long-term infusion of different dosage forms of propofol on lipid metabolism in patients with hyperlipidemia: a prospective, randomized controlled study
Phase 4
- Conditions
- hyperlipidemia
- Registration Number
- ChiCTR2400088910
- Lead Sponsor
- Guangyuan first people's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
(1) ASA grade ? - ?; (2) There is no limit on gender, and the age is between 14 and 65 years old; (3) Estimated operation time > 3 hours; (4) Preoperative serum triglyceride = 1.70mmol/l, cholesterol = 5.20mmol/l.
Exclusion Criteria
(1) Patients scheduled for hepatobiliary pancreatic surgery; (2) Preoperative use of drugs that affect blood lipids; (3) Preoperative abnormal liver function (alt>40u/l, ast>40u/l) or use of drugs that damage liver enzymes; (4) Preoperative history of pancreatitis; (5) Have a history of drug abuse or long-term drinking; (6) Serious mental illness; (7) Patients with intraoperative blood loss>20% of total blood volume or massive blood transfusion; (8) Body mass index (BMI)<20kg/m2,Or>29kg/m2.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Triglyceride;Total cholesterol;High-density lipoprotein cholesterol;Low density lipoprotein cholesterol;Apolipoprotein A1;Apolipoprotein B;
- Secondary Outcome Measures
Name Time Method C-reactive protein;Interleukin-6;