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临床试验/CTRI/2025/07/091403
CTRI/2025/07/091403尚未招募4 期

Comparing the efficacy of insulin lispro infusion vs Vellore regimen for optimizing perioperative blood sugar level in diabetic patients undergoing emergency surgery: A randomized clinical trial.

aarupadai veedu medical college and hospital1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2025年7月31日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
300
试验地点
1
主要终点
To Compare the efficacy of Vellore regimen vs insulin lispro infusion for optimizing perioperative blood sugar level in diabetic patients undergoing emergency surgery

研究概览

简要总结

After informed consent all the diabetic patients planned for surgery are included, their current glycemic status (Blood Sugar AC AND PC valve, HbA1c), Blood pressure, BMI and medication for Co-morbid are recorded. Group V Will be receiving regular insulin on titrated doses for control of blood sugar by vellore regimen , Group L Will be receiving lispro insulin infusion for control of blood sugar.

Plan in Pre-operative periodControl of Glycemic status with diabetic management plan, capillary blood glucose Level will be monitored regularly, fluid and electrolyte maintenance according to Individual patients will be done.

Intra-operative: For all patient’s capillary blood glucose level will be checked before induction, every hourly intra- operative blood sugar monitoring, change in blood  sugar valve will be adjusted with subcutaneous or by intravenous insulin. Plan to have individualized goal directed therapy.

Post OperativePlan to maintain glycemic status (Blood Sugar value of 6-10mmol per L), fluid and electrolytes control and insulin therapy for each patient will be monitor and

recorded for data collection.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • ASA 1,2,3 RBS greater than 100 mg per dl BMI LESS THAN 35.

排除标准

  • Patients unwilling to enroll for the study Patients with a history of allergy to the drugs used in the study.

结局指标

主要结局

To Compare the efficacy of Vellore regimen vs insulin lispro infusion for optimizing perioperative blood sugar level in diabetic patients undergoing emergency surgery

时间窗: 180 MINUTES

次要结局

  • To monitor serum electrolytes changes.
  • To monitor hypoglycaemic episodes.(180 MINUTES)

研究者

发起方
aarupadai veedu medical college and hospital
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr ezhilrajan

Aarupadai Veedu Medical College

研究点 (1)

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