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Comparing the effectiveness of combination therapy and monotherapy on quality of life in patients with persistent allergic rhinitis

Phase 2
Conditions
allergic rhinitis.
Vasomotor and allergic rhinitis
Registration Number
IRCT20200909048677N1
Lead Sponsor
Kashan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
56
Inclusion Criteria

Patients with allergic rhinitis who are symptomatic for more than 4 weeks and also more than 4 days a week
Existence of persistent allergic rhinitis during the last 2 years
Age 18-65 years

Exclusion Criteria

unwillingness to cooperate
Severe upper respiratory tract disease during the 6 weeks prior to the study
Nasal polyps or deviation of the nasal septum
Acute or chronic rhinosinusitis
smoking
Bronchial asthma
Pregnancy or breastfeeding
Taking antihistamines during the last 1 month
Use of systemic or topical corticosteroids
History of allergies to Montelukast or Des Loratadine

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Quality of life score. Timepoint: Once before starting treatment and once 6 weeks after starting treatment. Method of measurement: mini-RQLQ checklist.
Secondary Outcome Measures
NameTimeMethod
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