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临床试验/CTRI/2025/03/082598
CTRI/2025/03/082598已完成不适用

Estimation of salivary matrix metalloproteinases- 8 (MMP-8) and its correlation to periodontal inflamed surface(PISA) before and after non- surgical periodontal therapy

Shalini Kumari1 个研究点 分布在 1 个国家目标入组 42 人开始时间: 2025年3月26日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
42
试验地点
1
主要终点
to estimate salivary MMP-8 to PISA in individuals with healthy periodontium and

研究概览

简要总结

This is an interventional study where salivary MMP-8 and PISA values will be estimated in individuals with healthy periodontium and in periodontitis before and after 3 months of non-surgical periodontal therapy.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
35.00 Year(s) 至 55.00 Year(s)(—)
性别
All

入选标准

  • Patients with a minimum of 20 teeth.
  • Patients with no history of periodontal therapy in the last 6 months.
  • Subjects with no history of any kind of systemic diseases.

排除标准

  • Patients with history of smoking and tobacco chewing Pregnant or lactating women.
  • Patients on any kind of medications.

结局指标

主要结局

to estimate salivary MMP-8 to PISA in individuals with healthy periodontium and

时间窗: salivary MMP-8 and PISA values will be calculated at baseline and non surgical periodontal therapy will be carried out at baseline. After 3 months salivary MMP-8 and PISA will be calculated.

periodontitis before and after non-surgical periodontal therapy

时间窗: salivary MMP-8 and PISA values will be calculated at baseline and non surgical periodontal therapy will be carried out at baseline. After 3 months salivary MMP-8 and PISA will be calculated.

次要结局

  • Not applicable(Not applicable)

研究者

发起方
Shalini Kumari
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Shalini Kumari

KLE Academy of Higher Education and Research

研究点 (1)

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