Comparative study between magnesium sulphate versus dexamethasone as an adjuvant to 0.5 percent bupivacaine in supraclavicular brachial plexus block.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare and study the onset and duration of sensory and motor blockade of magnesium sulphate and dexamethasone as an adjuvant to 0.5% Bupivacaine in supraclavicular brachial plexus block
研究概览
简要总结
It is a prospective, randomised, double blinded comparative study to compare magnesium sulphate versus dexamethasone as Ana adjuvant to 0.5% Bupivacaine in supraclavicular brachial plexus block.
60 patients planned for upper limb surgeries below the shoulder will be divided into two groups of 30 patients each: Group A(dexamethasone) and Group B(magnesium sulphate)
Objectives include
To compare and study the onset of sensory blockade and motor blockade in both study groups.
To compare and study the duration of sensory analgesia and motor blockade in both study groups.
To compare the duration of post operative analgesia in both study groups.
To observe any side effects of both the drugs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade 1 and 2 fit patients.
- •Patients aged between 18-60 years of age.
- •Both male and female gender.
- •Patients posted for upper limb surgeries below shoulder.
- •Hemodynamically stable patients with all routine investigations within normal limits.
- •Written informed consent from the concerned patients.
排除标准
- •Patients who are not willing to participate in the study.
- •Patients with ASA grade 3 and above physical status.
- •Patients who are aged more than 60 years and less than 18 years of age.
- •Patients with known allergy to the study drugs.
- •Patients who are posted for emergency procedures.
- •Patients with bleeding disorders and those on anticoagulant therapy.
- •Infection at site of block.
- •Neuro deficit involving brachial plexus.
- •Pregnant women.
- •Patients with psychiatric, neurological, neuromuscular or cardiovascular disease or impaired hepatic or renal function.
结局指标
主要结局
To compare and study the onset and duration of sensory and motor blockade of magnesium sulphate and dexamethasone as an adjuvant to 0.5% Bupivacaine in supraclavicular brachial plexus block
时间窗: The sensory block will be evaluated by pin prick sensation and motor block will be assessed with the help of modified bromage scale after injection of study drugs. Vital parameters will be monitored every 5 mins for first 15 mins and every 15 mins till the end of surgery
次要结局
- To compare the duration of post operative analgesia in both study groups & observe any side effects of both the drugs(Duration of analgesia will be assessed post surgery & time to rescue analgesia will be assessed 2 hourly after surgery until intervention is required)
研究者
Dr Sabyasachi Mohapatra
Dr.D.Y.Patil Medical College, Hospital and Research Centre