GLP-1: Acute Effects on Kidney Function in Healthy Men

Not Applicable

Completed

• Conditions: Kidney Functional
• Interventions: Biological: Human GLP-1 (7-36) amide; Biological: Isotone NaCl

• Registration Number: NCT01333163
• Lead Sponsor: Jeppe Skov

Brief Summary

The purpose of this study is to investigate how Glucagon-Like Peptide 1 (GLP-1) affects kidney function in healthy young men. The hypothesis is that GLP-1 induces a positive effect on kidney hemodynamics.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-04-08
• Study First Submitted QC: 2011-04-08
• Study First Posted: 2011-04-11
• Study Start: 2011-05
• Status Verified: 2011-12
• Primary Completion: 2011-12
• Study Completion: 2011-12
• Last Update Submitted: 2011-12-14
• Last Update Posted: 2011-12-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

• Healthy young men

Exclusion Criteria

• Any chronic diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
GLP-1	Human GLP-1 (7-36) amide	-
Placebo	Isotone NaCl	-

Primary Outcome Measures

Name	Time	Method
Glomerular Filtration Rate	Every 20 minutes for 6 hours

Trial Locations

Locations (1)

Klinisk Institut, Afd. MEA, Aarhus Sygehus, NBG; 🇩🇰 Aarhus C, Denmark