A study to determine effects of magnesiumsulphate with Bupivacaine hydrochloride in spinal anaesthesia.
Phase 4
- Conditions
- Health Condition 1: K40-K46- HerniaHealth Condition 2: M15-M19- OsteoarthritisHealth Condition 3: N20-N23- Urolithiasis
- Registration Number
- CTRI/2024/02/062867
- Lead Sponsor
- Anupama Kumari
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Adult patients ranging from 18-65 years of age
2.Patients undergoing infra-umbilical surgeries
3.Patients belonging to ASA grade 1 and 2
Exclusion Criteria
1.Patients refusal, uncooperative patients or children
2.Patients with hepatic, renal, cardiac or respiratory problems.
3.Patients with localised site infections
4.Haematological, bleeding disorders and coagulopathies.
5.Known allergy to magnesium sulphate or other study drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prolongation of the onset and time to reach the highest level of sensory and motor blockade in spinal anesthesia.Timepoint: 1. Onset of Motor blockade after injection of drug intrathecally <br/ ><br>2. Onset, highest level and duration of sensory blockade after injection of drug intrathecally <br/ ><br>3. Hemodynamic stability at 0min, and then every 30 mins till end of surgery. <br/ ><br>4. Time of requirement of rescue analgesic in post-operative period.
- Secondary Outcome Measures
Name Time Method An easily available, inexpensive adjuvant to increase & improve spinal anesthesia profile.Timepoint: 1. 1. Onset of Motor blockade after injection of drug intrathecally <br/ ><br>2. Onset, highest level & duration of sensory blockade after injection of drug intrathecally <br/ ><br>3. Hemodynamic stability at 0min, & then every 30 mins till end of surgery. <br/ ><br>4. Time of requirement of rescue analgesic. <br/ ><br>5.Cost effectiveness <br/ ><br>6. Availability