A study to know the effects of Glutamine on oral mucositis caused by Chemo-radiotherapy treatment of throat cancer
Phase 3
- Conditions
- Health Condition 1: null- Cases of Carcinoma Oropharynx and Supraglottic Larynx with stage III and IV which are suitable for Radical Chemo-Radiotherapy
- Registration Number
- CTRI/2017/02/007772
- Lead Sponsor
- Bhagwan Mahaveer Cancer Hospital and Research Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Diagnosed cases of Stage III-IV of Squamous cell Carcinoma Oropharynx and Supraglottis, which are fit for radical Chemo-Radiotherapy treatment
Exclusion Criteria
•Primary site carcinoma Oral cavity, nasopharynx.
•History of previous radiotherapy to head neck region
•Abnormal LFT/RFT
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of oral mucositis between Glutamine arm and controlled armTimepoint: 2 years
- Secondary Outcome Measures
Name Time Method To compare the incidence and severity of DysphagiaTimepoint: 2 years;To compare the incidence of treatment breaksTimepoint: 2 years;To compare the weight loss during radiotherapyTimepoint: 2 years;To compare time of onset of oral mucositis in between the two armsTimepoint: 2 years