US Guided EOI Block Versus ESPB for Postoperative Analgesia in Laparoscopic Cholecystectomy

Not Applicable

Recruiting

• Conditions: Postoperative Pain
• Interventions: Other: Erector spinae plane block (ESPB); Other: External oblique intercostal (EOI) block

• Registration Number: NCT05272280
• Lead Sponsor: Assiut University

Brief Summary

To compare the efficacy of USG-guided bilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis that both External oblique intercostal fascial plane block and Erector spinae plane block are effective in providing post-operative analgesia.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-02-28
• Study First Submitted QC: 2022-02-28
• Study First Posted: 2022-03-09
• Study Start: 2022-05-01
• Status Verified: 2024-07
• Last Update Submitted: 2024-07-31
• Last Update Posted: 2024-08-02
• Primary Completion: 2025-01
• Study Completion: 2025-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age between 18 and 65 years with a body mass index (BMI) of 18-35 kg/m2,
• patients with the American Society of Anesthesiologists (ASA) physical status I/II,
• Patients scheduled for elective laparoscopic cholecystectomy.

Exclusion Criteria

• Allergy to local anaesthetics,
• Infection at the site of injection,
• Coagulopathy,
• Chronic pain syndromes,
• Prolonged opioid medication,
• Patients who received any analgesic 24 h before surgery.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Erector spinae plane block (ESPB)	Erector spinae plane block (ESPB)	-
External oblique intercostal (EOI) block	External oblique intercostal (EOI) block	-

Primary Outcome Measures

Name	Time	Method
Nalbuphine consumption in mg equivalent to morphine dose.	24 hours postoperatively	mg

Secondary Outcome Measures

Name	Time	Method
Heart Rate	Intraoperatively at 0, 5,10, 20, and 30 minutes. Then every 15 min thereafter till the end of surgery	beats /min
Mean Arterial Pressure	Intraoperatively at 0, 5,10, 20, and 30 minutes. Then every 15 min thereafter till the end of surgery	mmHg
Shoulder pain	24 hours postoperatively	Number of patients developing Shoulder pain
Numerical Rating Scale (NRS) at rest and when coughing	at 1, 2,4 , 8, 16 and 24 hours postoperatively	11-point scale where 0=no pain and 10=worst pain
Incidence of Postoperative nausea & vomiting (PONV)	24 hours postoperatively	Number of patients developing PONV
Analgesic drug consumption other than nalbuphine	24 hours postoperatively	in mg

Trial Locations

Locations (1)

Assiut University hospital; 🇪🇬 Assiut, Assiut, Asyut Governorate, Egypt,, Egypt