NCT02482909
Terminated
Not Applicable
A Prospective Randomized Study to Compare the Efficacy of Radiofrequency Ablation and Hepatic Resection as a Primary Treatment for Single Small Hepatocellular Carcinoma
ConditionsCarcinoma, Hepatocellular
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Carcinoma, Hepatocellular
- Sponsor
- Seoul National University Hospital
- Enrollment
- 68
- Primary Endpoint
- The patient survival
- Status
- Terminated
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this prospective randomized study is to compare the efficacy and safety of radiofrequency ablation and hepatic resection for small hepatocellular carcinomas with very homogeneous underlying conditions.
Investigators
Kyung-Suk Suh
Professor
Seoul National University Hospital
Eligibility Criteria
Inclusion Criteria
- •Age between 20 and 70 years
- •Child-Pugh class A (score 5-6)
- •Single hepatocellular carcinoma
- •Maximal diameter of the tumor from 2 to 4 cm when measured on MRI or CT (The diameter on MRI was measured prior to that on CT)
- •No previous treatment
- •Platelet count \> 80,000/mm3
Exclusion Criteria
- •HCC abutting main hepatic veins or the first branches of the main portal vein
- •HCC abutting vessels ≥ 0.5 cm
Outcomes
Primary Outcomes
The patient survival
Time Frame: From the intervention up to 5 years or until the death of the participant whichever came first
Secondary Outcomes
- The disease-free survival(From the intervention up to 5 years or until hepatocellular carcinoma recurrence whichever came first)
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