Effect of Epidural Opioid Administered in the First A Period on the Progress of Labour
Overview
- Phase
- Phase 4
- Intervention
- Fentanyl
- Conditions
- Anesthesia, Epidural
- Sponsor
- Medical University of Warsaw
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Pain intensity according to Numerical Rating Scale (NRS)
- Last Updated
- 7 years ago
Overview
Brief Summary
Epidural anesthesia is used to relieve labour pain which helps reduce labour stress, increase comfort and improve cooperation with medical personnel. Administering opioid into the epidural space before cervical dilation of 4cm in the primigravida or 3cm in the multiparous can effectively reduce the pain levels with no effect on the labour progress. The aim of the study is to compare different opioids administered in this early labour stage.
Investigators
Jan Biławicz
Principal Investigator
Medical University of Warsaw
Eligibility Criteria
Inclusion Criteria
- •parturient in labour without cervical dilation and regular uterine contractions
Exclusion Criteria
- •no consent
- •known allergy to administered opioid
- •contraindications to epidural analgesia
- •coagulopathies including platelet count of less than 100,000
- •spine surgery in past
Arms & Interventions
Fentanyl
100mcg Fentanyl administered into epidural space during regular contractions before cervical dilation
Intervention: Fentanyl
Sufentanyl
10mcg sufentanyl administered into the epidural space during regular contractions before cervical dilation
Intervention: Sufentanil
Outcomes
Primary Outcomes
Pain intensity according to Numerical Rating Scale (NRS)
Time Frame: up to 24 hours
till 4cm cervical dilation in primigravida or 3cm multiparous
Secondary Outcomes
- Fetal heart rate(up to 24 hours)
- Blood pressure parturient(up to 24 hours)
- Heart rate of parturient(up to 24 hours)