The Association Between Epidural Labor Analgesia and Pregnancy Outcomes
Overview
- Phase
- Not Applicable
- Intervention
- Ropivacaine Hydrochloride, Sufentanil
- Conditions
- Labor Pain
- Sponsor
- Deng Dongrui
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Labor duration
- Last Updated
- 7 years ago
Overview
Brief Summary
Labor analgesia can alleviate intrapartum pain, in the importance of the delivery is very obvious.But some researches think labor analgesia may affect the progress of labor, increase the cesarean section rate.This research adopts the epidural anesthesia to study labor analgesia effects on delivery outcomes and long-term emotional and psychological effects on the mothers. Besides, we also want to study the effect of exercise during pregnancy on the mode of delivery.
Investigators
Deng Dongrui
professor,chief doctor
Tongji Hospital
Eligibility Criteria
Inclusion Criteria
- •healthy and full term pregnant women
Exclusion Criteria
- •the pregnant women with complications
Arms & Interventions
Epidural analgesia during labor
The epidural analgesia technique was used to maintain analgesia for parturients who request labor analgesia.First, we injected a test dose of 5ml 1% lidocaine . If not adverse effects were observed 10 minutes after the test dose, the parturient then received a bolus injection of an initial dose of 8-10 ml mixed liquids of 0.075% ropivacaine and 0.2ug/ml sufentanil citrate. We then connected the epidural catheter with a patient-controlled epidural analgesia (PCA) pump, which provided patients the same mixed solution at 8-10ml/h until the delivery of neonates.
Intervention: Ropivacaine Hydrochloride, Sufentanil
Outcomes
Primary Outcomes
Labor duration
Time Frame: At the end of the delivery
Duration of three stages of labor.
Secondary Outcomes
- 1 minute Apgar index(1 minute after the infant is born)
- 5 minute Apgar index(5 minutes after the infant is born)
- Visual Analogue Scores(VAS)(5min before analgesia;5min,15min, 30min,60min after analgesia; at the time of latent phase, active phase, full dilation of the cervix, crowning of head, and laceration repair.)
- Modified Bromage scores(5min before analgesia;5min,15min, 30min,60min after analgesia; at the time of latent phase, active phase, full dilation of the cervix, crowning of head, and laceration repair.)
- Postpartum depression(3 days after delivery,6 weeks after delivery, 3 months after delivery, 6 months after delivery, 1 year after delivery.)
- The mode of delivery(At the end of delivery)