The Association Between Epidural Labor Analgesia and Pregnancy Outcomes
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Labor duration
研究概览
简要总结
Labor analgesia can alleviate intrapartum pain, in the importance of the delivery is very obvious.But some researches think labor analgesia may affect the progress of labor, increase the cesarean section rate.This research adopts the epidural anesthesia to study labor analgesia effects on delivery outcomes and long-term emotional and psychological effects on the mothers. Besides, we also want to study the effect of exercise during pregnancy on the mode of delivery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 50 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •healthy and full term pregnant women
排除标准
- •the pregnant women with complications
研究组 & 干预措施
Epidural analgesia during labor
The epidural analgesia technique was used to maintain analgesia for parturients who request labor analgesia.First, we injected a test dose of 5ml 1% lidocaine . If not adverse effects were observed 10 minutes after the test dose, the parturient then received a bolus injection of an initial dose of 8-10 ml mixed liquids of 0.075% ropivacaine and 0.2ug/ml sufentanil citrate. We then connected the epidural catheter with a patient-controlled epidural analgesia (PCA) pump, which provided patients the same mixed solution at 8-10ml/h until the delivery of neonates.
干预措施: Ropivacaine Hydrochloride, Sufentanil (Drug)
结局指标
主要结局
Labor duration
时间窗: At the end of the delivery
Duration of three stages of labor.
次要结局
- 1 minute Apgar index(1 minute after the infant is born)
- 5 minute Apgar index(5 minutes after the infant is born)
- Visual Analogue Scores(VAS)(5min before analgesia;5min,15min, 30min,60min after analgesia; at the time of latent phase, active phase, full dilation of the cervix, crowning of head, and laceration repair.)
- Modified Bromage scores(5min before analgesia;5min,15min, 30min,60min after analgesia; at the time of latent phase, active phase, full dilation of the cervix, crowning of head, and laceration repair.)
- Postpartum depression(3 days after delivery,6 weeks after delivery, 3 months after delivery, 6 months after delivery, 1 year after delivery.)
- The mode of delivery(At the end of delivery)
研究者
Deng Dongrui
professor,chief doctor
Tongji Hospital