Intradialytic hypotension prevention by intermittent infusion HDF
- Conditions
- Chronic Kidney Failure
- Registration Number
- JPRN-UMIN000013816
- Lead Sponsor
- Koda Medical and Dialysis Clinic
- Brief Summary
Sixty eight patients completed the study. Nine were dropouts. During I-HDF, interventions for symptomatic hypotension were reduced significantly from 4.5 to 3.0 (per person-month, median) and intradialytic systolic blood pressure was 4 mmHg higher on average. The heart rate was lower during I-HDF than HD in the later session. I-HDF could reduce interventions for IDH. It is accompanied with the increased intradialytic blood pressure and the less tachycardia, suggesting less sympathetic stimulation occurs. Thus, I-HDF could be beneficial for some hypotension-prone patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Not provided
# Cardiovascular or cerebrovascular event in the last 3 month. # Obvious inflammatory diseases. # Obvious and active infective diseases # Systolic blood pressure rise over 150mmHg during HD. # On dialyser with membrane area of greater than 2.2 square-meter, or less than 0.8 square-meter. # On combination therapy with adsorptive device (e.g. Lixcel)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method