Oculocardiac Reflex Brain Wave Monitor
- Conditions
- BradycardiaStrabismus
- Interventions
- Device: non-invasive monitor
- Registration Number
- NCT03663413
- Lead Sponsor
- Alaska Blind Child Discovery
- Brief Summary
Oculocardiac reflex during routine strabismus surgery was prospectively observed in association with routine brain wave monitoring.
Providence Hospital institutional review board (IRB) approved this observational study without need for consent.
- Detailed Description
Introduction: The oculocardiac reflex (OCR), bradycardia that occurs during strabismus surgery, is blocked by anticholinergics and enhanced by opioids and dexmedetomidine. Two recent studies suggest that deeper inhalational anesthesia monitored by bispectral index (BIS) protects against OCR; the investigators wondered if our data correlated similarly.
Methods: In an ongoing, prospective study of OCR elicited by 10-second, 200 gram square-wave traction on extraocular muscles (EOM) from 2009 to 2013, anesthetic depth was estimated in cohorts using either BIS or Narcotrend monitors. The depth of anesthesia was deliberately varied between first and second EOM tested.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 188
- all
- those receiving anticholinergic medications
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Narcotrend non-invasive monitor Monitored with Narcotrend monitor in addition to other conventional monitors of blood pressure, ECG, oxygen saturation and anesthetic agent concentration. BIS non-invasive monitor Monitored with BIS (bispectral index) monitor in addition to other conventional monitors of blood pressure, ECG, oxygen saturation and anesthetic agent concentration.
- Primary Outcome Measures
Name Time Method heart rate change intraoperative 10 seconds bradycardia with extra ocular muscle tension
- Secondary Outcome Measures
Name Time Method