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临床试验/NCT01714362
NCT01714362已完成不适用

Prediction of Oculocardiac Reflex in Relationship to Autonomic Nervous System Activity, Mesured With the Use of ECG HRV Analysis.

Medical University of Gdansk1 个研究点 分布在 1 个国家目标入组 52 人开始时间: 2009年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
52
试验地点
1
主要终点
oculocardiac reflex occurence in relation to autonomic system activity

研究概览

简要总结

Pulling the eyeball during ophthalmic surgery provokes decrease in heart rate. This phenomenon is called oculocardiac reflex. In some patients asystole may occur. Other cardiac features of this reflex include hypotension, dysrhythmias, atrioventricular block. These cardiovascular disturbances may lead to decreased perfusion and ischemia of vital organs. Patients with existing cardiovascular disease are in risk of complications. Cardiovascular system is mainly innervated with autonomic nervous system (ANS). Sympathetic/parasympathetic activity may be determined by Heart Rate Variability (HRV). HRV analysis based on short 5 minutes electrocardiography has been found useful for prediction of hypotension and bradycardia during induction of general anaesthesia and during spinal block. The aim of this study is to verify whether it is possible to predict oculocardiac reflex with the use of HRV analysis for ANS activity assessment, measured prior to the ophthalmic surgery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • planned surgery
  • over 18 years of age
  • surgery under general anaesthesia

排除标准

  • urgent surgery
  • under 18 years of age and over 65
  • patients with generalised, nontreated disease
  • patients receiving beta blockers or calcium channel blocker
  • diabetic patients
  • patients operated under peri or retrobulbar anaesthesia

结局指标

主要结局

oculocardiac reflex occurence in relation to autonomic system activity

时间窗: perioperatively - about 2 hours

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Magdalena Wujtewicz

assistant professor

Medical University of Gdansk

研究点 (1)

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