Post Cardiac Arrest Neuroprognostication Using the Diameter of Optic Nerve Sheath Via Ocular ultRAsound
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Optic nerve sheath diameter
研究概览
简要总结
This study investigates the relationship between optic nerve sheath diameter and increased intracranial pressure and its effect on neurologic outcome in post-cardiopulmonary arrest patients.
详细描述
This study involves patients who have experienced either an in-hospital or out-of-hospital cardiopulmonary arrest, and who meet the 2015 American Heart Association (AHA) inclusion/exclusion criteria for targeted temperature management [i.e., they are comatose or exhibit no meaningful response to verbal commands with return of spontaneous circulation (ROSC) after cardiac arrest]. After induction of hypothermia protocol after cardiopulmonary arrest (i.e., targeted temperature management), patients will undergo ocular ultrasound at three time points.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient ≥ 18 years of age
- •Patient has experienced either an in-hospital or out-of-hospital cardiopulmonary arrest
- •Patient is comatose or exhibits lack of meaningful response to verbal commands with return of spontaneous circulation (ROSC) after cardiopulmonary arrest
- •Patient must meet all inclusion criteria as deemed by physician and the 2015 American Heart Association standards for targeted temperature management (TTM) following cardiopulmonary arrest
排除标准
- •Patient < 18 years of age
- •Patient does not meet inclusion criteria for targeted temperature management (TTM)
- •Unable to obtain consent from Legal Authorized Representative (LAR)
- •Patient has a Do Not Resuscitate (DNR) order or a Do Not Intubate (DNI) order at the time of consent
- •Patient has uncontrollable bleeding
- •Patient is able to follow verbal commands
- •Patient has another medical condition creating increased ocular pressure, as deemed by physician
结局指标
主要结局
Optic nerve sheath diameter
时间窗: 0-6 hours after hypothermic protocol initiation
Optic nerve sheath diameter within 6 hours of hypothermic protocol initiation
次要结局
- Optic nerve sheath diameter(24-36 hours after hypothermic protocol initiation)