Hormonal Influences on Diuresis

Not Applicable

Completed

• Conditions: LUTS; Diuresis; Nocturia; Menopause
• Interventions: Diagnostic Test: ICIQ FLUTS Questionaires; Diagnostic Test: Frequency Volume Chart; Diagnostic Test: Renal Function Profile; Diagnostic Test: Blood Analysis

• Registration Number: NCT04891926
• Lead Sponsor: University Hospital, Ghent

Brief Summary

The aim of this study was to observe the effect of hormonal treatment (oral or transdermal substitution therapy) on diuresis (salt and water diuresis) and lower urinary tract symptoms (LUTS) in postmenopausal women

Detailed Description

Not available

Study Timeline

• Study Start: 2015-05-01
• Primary Completion: 2018-09-30
• Study Completion: 2018-09-30
• Status Verified: 2021-04
• Study First Submitted: 2021-05-04
• Study First Submitted QC: 2021-05-17
• Last Update Submitted: 2021-05-17
• Study First Posted: 2021-05-19
• Last Update Posted: 2021-05-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

• Patients in a postmenopausal state wo wanted to start treatment for menopausal symptoms (hot flushes etc)

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Hormonal therapy	Blood Analysis	Patients choosing to start hormoanl treatment using ural or transdermal estrogen.
Hormonal therapy	ICIQ FLUTS Questionaires	Patients choosing to start hormoanl treatment using ural or transdermal estrogen.
Hormonal therapy	Frequency Volume Chart	Patients choosing to start hormoanl treatment using ural or transdermal estrogen.
Hormonal therapy	Renal Function Profile	Patients choosing to start hormoanl treatment using ural or transdermal estrogen.

Primary Outcome Measures

Name	Time	Method
Change of HT on nocturnal frequency	6 months	Change of nocturnal frequency by 1 nocturnal void after 6 months of hormonal treatment.

Secondary Outcome Measures

Name	Time	Method
Effect on nocturnal urine production	6 months	Change of the nocturnal urine production by hormonal treatment by the volume of one micturition (+- 200ml)