China STEMI Care Project

• Conditions: ST-Elevation Myocardial Infarction
• Interventions: Other: in-hospital process optimization; Other: the whole-city STEMI care network construction; Other: PPCI hospital-based regional STEMI transfer network construction

• Registration Number: NCT03821012
• Lead Sponsor: Peking University First Hospital

Brief Summary

The China ST-elevation myocardial infarction (STEMI) Care Project (CSCAP) aims to improve the reperfusion treatment rate and shorten the total duration of myocardial ischemia by establishing a regional STEMI treatment network covering the whole-city region, whole-city population, and whole-disease process step by step. The CSCAP is a prospective, multicenter registry involving three phases. A total of 18 provinces, 4 municipalities, and 2 autonomous regions in China were included. Patients with STEMI who met with the third acute myocardial infarction definition and the Chinese STEMI diagnosis and treatment guidelines were enrolled and the estimated number is over 50,000. Phase 1 (CSCAP-1) focused on the in-hospital process optimization of primary percutaneous coronary intervention (PPCI) hospitals. Phase 2 (CSCAP-2) focused on the PPCI hospital-based regional STEMI transfer network, including emergency medical services and non-PPCI hospitals. Phase 3 (CSCAP-3) focused on the whole-city STEMI care network construction by promoting chest pain center accreditation. Systematic data collection, assessment of quality of care, and subsequent improvement were implemented throughout the project to continuously improve the quality of care for patients with STEMI.

CSCAP is the first project that focused on establishing a regional STEMI emergency care network in China to help understand the condition of STEMI care in China extensively. Moreover, its objective was to optimize the quality of STEMI care through in-hospital process optimization (2012-2013), PPCI hospital-based regional STEMI transfer network construction (2015-2018), and construction of the whole-city STEMI care network step by step (2018-2021). However, hospitals were not randomly selected in CSCAP, which might be because of the lack of representatives to some degree. Alternatively, it focused on providing a tailored quality-of-care improvement plan based on the conditions of different regions.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Status Verified: 2019-01
• Study First Submitted: 2019-01-22
• Study First Submitted QC: 2019-01-28
• Last Update Submitted: 2019-01-28
• Study First Posted: 2019-01-29
• Last Update Posted: 2019-01-29
• Primary Completion: 2021-12
• Study Completion: 2021-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50000

Inclusion Criteria

• STEMI patients

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
CSCAP-1	in-hospital process optimization	STEMI with symptom onset within 12 h regardless of whether receiving reperfusion or symptom onset within 12-24 h of needing PPCI
CSCAP-3	the whole-city STEMI care network construction	STEMI patients with symptom onset within 30 days
CSCAP-2	PPCI hospital-based regional STEMI transfer network construction	STEMI patients with symptom onset within 30 days

Primary Outcome Measures

Name	Time	Method
the total duration of myocardial ischemia	12 hours	Median time from symptom onset to target vessel open in STEMI patients
the reperfusion treatment ratio	12 hours	the ratio of primary PCI plus thrombolysis usage in STEMI patients

Trial Locations

Locations (1)

Peking University First Hospital; 🇨🇳 Beijing, Beijing, China